England host Ukraine at Wembley in their second World Cup qualifier on Tuesday having won the opener 5-0 in Moldova.
The Three Lions are looking to continue their winning start to Group H against the Eastern Europeans, who are hoping to show there is life after Andriy Shevchenko.
John Terry's absence with an ankle injury picked up in the closing stages of Friday's clash with Moldova means Chelsea team-mate Gary Cahill will likely come in to partner Joleon Lescott at centre-back.
Lampard's second goal against Moldova showed he still has the knack of timing his runs into the penalty area to perfection and his movement could again be key to unlocking Ukraine's defence. The experienced Tymoshchuk's job will be to keep an eye on the Chelsea midfielder and prevent him getting the space to do any damage.
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England manager Roy Hodgson is confident he has the players to maintain their winning start to the World Cup qualifying campaign despite mounting injury problems for Tuesday's match against Ukraine at Wembley.
The absences mean Liverpool teenager Raheem Sterling, Tottenham's Jake Livermore and Southampton's Adam Lallana have all been added to the squad as cover. Yet Hodgson has no plans to throw any of the trio in at the deep end. He said: "It was a good opportunity to invite some young players to come in and be part of the atmosphere."
He continued: "We still have enough good players to be able to deal with the game, but it's always good when you have the chance to invite these players to come in and be a part of the atmosphere and see how things are."
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